Born in St. Louis on June 29, 1923, Mrs. Simon grew up in, Steubenville, Ohio, where she graduated high school. She earned her bachelor of arts degree at University of Michigan in 1944 and moved with her family (parents, Lew and Bluma Rubenstein, and brother, Farrell) to Pittsburgh. She met her husband, Seymour Simon, in Pittsburgh in 1945 while she was working at United Press as a reporter and Seymour was finishing his tour of duty in the Army; they married in 1946. They moved to New York City where Mrs. Simon worked for Time Magazine. After raising two children, Neil and Rob, she returned to work as an elementary school teacher and later became a school district coordinator of math curriculum. She and Seymour retired to Tucson in 1986; they were married 72 years until his death in April 2019.
Survivors include her brother, Farrell (Nancy) Rubenstein of Pittsburgh; sons, Neil (Diane) Simon of Tucson and Rob (Marisol) Simon of Denver; and four grandchildren.
Family member Cantor Patti Linsky officiated at a private service.