Slepian is a cardiologist, inventor, entrepreneur and educator. At the University of Arizona, he serves as professor of medicine, professor and associate department head of biomedical engineering, professor of materials science and engineering, professor of medical imaging, McGuire Scholar in the Eller College of Management and a member of the Sarver Heart Center and BIO5 Institute. Slepian is founder and director of the Arizona Center for Accelerated Biomedical Innovation, which focuses on developing novel solutions for unmet medical needs.
He is a named inventor on more than 50 issued patents and applications in the fields of vascular biology, polymeric biomaterials, local drug delivery and artificial organs, and he has commercialized a range of inventions. He and ACABI have collaborated with the UA Tech Launch Arizona program to commercialize several technologies through startups. Slepian is a fellow of the National Academy of Inventors and president of the International Society for Mechanical Circulatory Support.